Low renin hypertension

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Low-renin and nonmodulating essential hypertension.

Low-renin hypertension (LREH) accounts for an important subset of the hypertensive human population and is associated with salt-sensitivity and diuretic response and is also common in black patients. An interesting finding in LREH is the presence of normal plasma aldosterone levels.1,2 The ratio of plasma aldosterone to renin activity is used to screen for adrenal adenomas and hyperplasia3 and ...

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Bimodal aldosterone distribution in low-renin hypertension.

BACKGROUND In low-renin hypertension (LRH), serum aldosterone levels are higher in those subjects with primary aldosteronism and may be lower in those with non-aldosterone mineralocorticoid excess or primary renal sodium retention. We investigated the hypothesis that the frequency distribution of aldosterone in LRH is bimodal. METHODS Of the 3,532 attendees at the sixth examination cycle of t...

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Familial aggregation of low-renin hypertension.

Low-renin hypertension, representing roughly one quarter of all essential hypertension, is widely recognized by distinct physiological features, including salt-sensitivity, diuretic- responsiveness, and a favorable natural history. Although certain demographic features including age, ethnicity, and diabetes mellitus predispose to low-renin hypertension, these factors account for only a minority...

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Does Extremely Low Birth Weight Predispose to Low-Renin Hypertension?

Low birth weight and prematurity are risk factors for hypertension in adulthood. Few studies in preterm or full-term born children reported on plasma renin activity (PRA). We tested the hypothesis that renin might modulate the incidence of hypertension associated with prematurity. We enrolled 93 prematurely born children with birth weight <1000 g and 87 healthy controls born at term, who were a...

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Primary aldosteronism and low-renin hypertension: a continuum?

Primary aldosteronism (PA) was first described by Jerome Conn almost 60 years ago, and is thus sometimes called Conn’s syndrome. Although Conn believed that PA may constitute 20% of all hypertension, within a decade of his initial findings, it was thought (and taught) that PA was relatively benign, accounted for <1% of hypertension, with hypokalaemia required for diagnosis, none of which we now...

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ژورنال

عنوان ژورنال: Indian Journal of Endocrinology and Metabolism

سال: 2012

ISSN: 2230-8210

DOI: 10.4103/2230-8210.100665